CANINE LYMPHOMA (UNTREATED)

Study to Evaluate the Safety and Efficacy of Rabacfosadine, Vincristine, Cyclophosphamide, Doxorubicin and Prednisone in Dogs with Untreated Lymphoma

Craig A Clifford DVM, MS, DACVIM (Oncology), Kristen Kicenuik, DVM, DACVIM (Oncology), Christine Mullin, VMD, Diplomate ACVIM (Oncology), and Rebecca Risbon, VMD, DACVIM (Oncology)
Investigators

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Lymphoma, the most common hematopoietic tumor of dogs, is an aggressive disease. While the majority of dogs will respond to cytotoxic chemotherapy utilizing a standard multi-agent (e.g. CHOP-based) approach, greater than 95% of dogs will relapse.

Study Description

This study will evaluate the safety and efficacy of TANOVEA®-CA1 when combined with vincristine, cyclophosphamide, doxorubicin, and prednisone (T-CHOP) in dogs with untreated lymphoma. TANOVEA-CA1 received conditional approval for the treatment of canine lymphoma, which means that when used according to the label, the drug is safe and has a “reasonable expectation of effectiveness” for treating lymphoma in dogs. This study may provide information on a multi-drug treatment protocol that may result in improved outcomes for dogs with multicentric lymphoma.

TANOVEA-CA1 is provided at no cost. The other costs associated with treatment, including staging and treatment with other drugs (vincristine, cyclophosphamide, doxorubicin, and prednisone), are the owner’s responsibility.

Inclusion Criteria

  • Dogs with lymphoma who have not been previously treated
  • Must be at least 1 year old
  • Must be otherwise healthy
  • Must have adequate organ function
  • West Highland White Terrier Breed is excluded from the study

Client Benefits

Clients participating in this study will be provided rabacfosadine at no cost.

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For more information, please contact us:

P: (610) 296-2099

E: [email protected]